Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan
نویسندگان
چکیده
منابع مشابه
Group B Streptococcus Evades Host Immunity by Degrading Hyaluronan.
In response to tissue injury, hyaluronan (HA) polymers are cleaved by host hyaluronidases, generating small fragments that ligate Toll-like receptors (TLRs) to elicit inflammatory responses. Pathogenic bacteria such as group B Streptococcus (GBS) express and secrete hyaluronidases as a mechanism for tissue invasion, but it is not known how this activity relates to immune detection of HA. We fou...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2015
ISSN: 1931-3128
DOI: 10.1016/j.chom.2015.11.001